ØUseful in management of metabolic disorders like Diabetes mellitus
ØUseful in diseases of liver
ØUseful in all gynecological problems involving excessive menstrual bleeding
ØAlleviates the pain and discomfort associated with menstrual bleeding
ØA good hypotensive agent
Common Name:
Chinese salacia
Sanskrit Name:
Saptachakra: As its roots bear seven circles
Swarnamoola: As its roots are covered by golden colored layer
Lt. Name:
Salacia Chinensis – Hippocrateaceae
Bio energetics:
Rasa (Taste) – Kashaya (Astringent); Tikta (Bitter)
Guna (Characteristics)- Laghu (Light); Ruksha (un-unctuous); Teekshna (Sharp in action)
Veerya (Potency)- Ushna (Hot)
Vipaka (Post digestion effect)- Katu (Pungent)
Chemical composition:
The main chemical constituents present in Saptarangiare 1,3-diketone, fats, rubber, Dulcitol, Mangiferin, Flobetanin, Glycocidal tannins and leucopelargonidin.
Effect on Tridosha (Three bio humors):
Saptachakra pacifies Kapha and Pitta Doshas so it can be used in all the diseases which originate from aggravation of Kapha/ Pitta or Kapha- Pitta.
Actions according to Ayurveda:
- Madhumehahari: Saptarangi is useful in management of metabolic disorders like Diabetes mellitus.
- Yakrudrogahara: Saptarangi is useful in diseases of liver.
- Rajorodham: Saptarangi is useful in all gynecological problems involving excessive menstrual bleeding
- Rajah krichchham nashyet: Saptarangi alleviates the pain and discomfort associated with menstrual bleeding.
Medicinal value:
- In the course of studies on anti-obese and antidiabetogenic principles in medicinal foodstuffs, it was found that the methanolic extract from the stems of Salacia chinensis (Hippocerateaceae) showed potent anti-hyperglycemic effects in oral sucrose or maltose-loaded rats, inhibitory effects on intestinal ?-glucosidase, rat lens aldose reductase, formation of Amadori compounds and advanced glycation end-products, nitric oxide production from lipopolysaccharide-activated mouse peritoneal macrophage, and radical scavenging activities. Those in vivo and in vitro biological activities were compared with those of S. oblonga and S. reticulata.
- Biological activities of Salacia chinensis: The quality evaluation guided by ?-glucosidase inhibitory activity: Yoshikawa Masayuki; Pongpiriyadacha Yutana; Kishi Akinobu; Kageura Tadashi; Tao Wang; Morikawa Toshio; Matsuda Hisashi ;
- The S. chinensis extract was investigated for hypotensive activity in anesthetized female rats in estrus, and for vasodilator activities on isolated thoracic aortic rings in vitro. Results showed that intravenous injection of S. chinensis extract (4-120 mg/kg) caused a decrease in mean arterial blood pressure and heart rate of anesthetized rats in a dose-dependent manner. These effects were not blocked by atropine, a muscarinic receptor antagonist or propranolol, a
-adrenergic receptor antagonist. For the in vitro preparation, the S. chinensis extract (0.01-0.3 mg/ml) caused vasodilatation of the thoracic aortic rings pre-constricted with phenylephrine in a dose-dependent manner. These effects persisted in the presence of atropine, propranolol or both of atropine and propranolol. However, when NG-nitro-L-arginine, a nitric oxide synthase inhibitor, was added or removal of vascular endothelium, the vasodilator activity of the S. chinensis extract on the thoracic aortic ring disappeared. These results suggest that the n-butanol extract from stems of Salacia chinensis possesses a hypotensive effect. The mechanism involved may be an indirect effect by stimulated release of nitric oxide from vascular endothelial cells and causes vasodilatation.
- HYPOTENSIVE EFFECT OF N-BUTANOL EXTRACT FROM STEM OF SALACIA CHINENSIS IN RATS C. Jansakul, N. Jusapalo, S. Mahattanadul
- Present study was undertaken to ascertain the hepatoprotective effect of root bark extract of Salacia chinensis. Ethanolic extract of dried bark of Salacia chinensis was evaluated and subjected for hepatoprotective activity in Wistar strain of albino rats of either sex against CCl 4 induced hepatic damage. SGOT, SGPT, ALP and Total Bilirubin were used as biochemical marker for assessment of the activity. The increased serum level of enzymes SGOT, SGPT, ALP and bilirubin were monitored in rats exposed with carbon tetrachloride, which were very much reduced in the animals treated with the ethanolic extract. On the basis of above results it could be concluded that ethanolic extract showed significant hepatoprotective activity against carbon tetrachloride induced hepatic damage.
- Hepatoprotective activity of ethanolic extract of root bark of Salacia chinensis Asuti Naveen K. L. E’S College of Pharmacy, Ankola, Karnataka, India
Useful part:
Roots
Doses:
Powder: 3-5 gm; Deoction: 50-100 ml
Saptarangi
