Medicinal value:

• Kasani is well known for its toxicity to internal parasites. Studies indicate that ingestion of Kasani by farm animals results in reduction of worm burdens.  
  
• "Individual administration of three tanniferous forage plants to lambs artificially infected with Haemonchus contortus and Cooperia curticei.” Vet Parasitol. 146 (1-2): 123–34. 2007-05-15.
• "The use of chicory for parasite control in organic ewes and their lambs.” Parasitology. 134 (Pt 2): 299–307. February 2007.
• "The effect of chicory (Cichorium intybus) and sulla (Hedysarum coronarium) on larval development and mucosal cell responses of growing lambs challenged with Teladorsagia circumcincta.” Parasitology
• Antiallergic effects: Kasani - Cichorium intybus inhibits mast cell-mediated immediate-type allergic reactions in vivo and in vitro.
  
• Kim, H. M., Kim, H. W., Lyu, Y. S., Won, J. H., Kim, D. K., Lee, Y. M., Morii, E., Jippo, T., Kitamura, Y., and An, N. H. Inhibitory effect of mast cell-mediated immediate-type allergic reactions by Cichorium intybus. Pharmacol Res 1999; 40(1):61-65.
• Antihyperlipidemic effects: Inulin decreases serum triglycerides by decreasing fatty acid synthesis and reducing production of low density lipoproteins (VLDL).
  
• Williams, C. M. Effects of inulin on lipid parameters in humans. J Nutr 1999; 129(7 Suppl):1471S-1473S.
• Anti-inflammatory effects: Kasani has been found to inhibit prostaglandin E (2) and cyclooxygenase 2 (COX-2). 
  
• Cavin, C., Delannoy, M., Malnoe, A., Debefve, E., Touche, A., Courtois, D., and Schilter, B. Inhibition of the expression and activity of cyclooxygenase-2 by chicory extract. Biochem Biophys Res Commun 2-18-2005; 327(3):742-749.
• Antineoplastic effects: Kasani derived beta (2-1) fructans have been shown to exert cancer protective effects in animal models. 
  
• Pool-Zobel, B. L. Inulin-type fructans and reduction in colon cancer risk: review of experimental and human data. Br J Nutr 2005; 93 Suppl 1:S73-S90.
• Hughes, R. and Rowland, I. R. Stimulation of apoptosis by two prebiotic chicory fructans in the rat colon. Carcinogenesis 2001; 22(1):43-47.
• Hypoglycemic effect: One animal study concluded dietary inulin-type fructans extracted from Kasani root may modulate the production of peptides, such as incretins, by endocrine cells present in the intestinal mucosa. This effect may play a role in the management of obesity and diabetes through their capacity to promote secretion of endogenous gastrointestinal peptides involved in appetite regulation.
  
• Delzenne, N. M., Cani, P. D., Daubioul, C., and Neyrinck, A. M. Impact of inulin and oligofructose on gastrointestinal peptides. Br J Nutr 2005; 93 Suppl 1:S157-S161. 
• Immunostimulatory activity: Oligofructose and inulin, selective fermentable chicory fructans, have been shown to stimulate the growth of bifidobacteria, which are regarded as beneficial strains in the colon. 
  
• Chow, J. Probiotics and prebiotics: A brief overview. J Ren Nutr 2002; 12(2):76-86.
• Reddy, B. S. Possible mechanisms by which pro- and prebiotics influence colon Carcinogenesis and tumor growth. J Nutr 1999; 129(7 Suppl):1478S-1482S.
• Reddy, B. S. Prevention of colon cancer by pre- and probiotics: evidence from laboratory studies. Br J Nutr 1998; 80(4):S219-S223. 

Useful part:

Leaves, roots, Seeds

Doses:

Juice of leaves: 10-20 ml; Powder of roots: 3-6gm; Powder off seeds: 3-6 gm

Some combinations with Kasni:

Arka Kasani

Ayurveda Herbs