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Auto immune Diseases 
According to modern science here are the reasons why auto immune diseases appear:
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Immunological factors
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Genetic factors
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Microbial factors But how does these factors work to initiate an autoimmune response is not known. There are different theories, but alas!! No one is able to explain the whole phenomenon. According to Ayurveda all this happens because of the production of a poisonous substance “Ama” which results from incomplete digestion and assimilation of the food articles. These food articles may be solid liquid or gaseous. All factors that can disturb digestion and assimilation are responsible for auto immune diseases like:
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Taking excess of water
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Untimely eating
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Suppressing natural urges
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Day sleeping and night working
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Mental set up inflicted with grief, worry, fear, and anger,
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Antibiotics, alcohol, caffeine, corticosteroids, non-steroidal anti-inflammatory drugs,
- Food preservatives and additives, refined carbohydrates,
Pathogenesis:
Joints:
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Inflammation of the involved joint
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Transient and migratory pain,
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Deformity and contracture of the joint
Skin:
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Photo sensitive rashes
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Loss of body hair
Kidneys:
The conditions are worst when the kidneys get involved, as now body starts losing protein with the urine and urea resides inside it.
Nervous system:
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Mild psychotic disturbance or epilepsy,
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Depression and Memory loss
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Un-oriented body movements,
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Loss of senses or activity in either half of the body,
Cardiopulmonary system:
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Impaired ventilation and diffusion,
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Pain behind the sternum radiating to shoulder and neck aggravating with deep breath and movements
Besides this involvement of eyes, liver or the receptors of nerve endings in muscles is also noticed.
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